Concept information
Preferred term
Calcimycin
Type
-
Topical Descriptor
Broader concept
Entry terms
- A 23187
- A-23187
Scope note
- An ionophorous, polyether antibiotic from Streptomyces chartreusensis. It binds and transports CALCIUM and other divalent cations across membranes and uncouples oxidative phosphorylation while inhibiting ATPase of rat liver mitochondria. The substance is used mostly as a biochemical tool to study the role of divalent cations in various biological systems.
History note
- 91(75); was A 23187 1975-90 (see under ANTIBIOTICS 1975-83)
In other languages
-
Finnish
-
A-23187
-
Swedish
URI
http://www.yso.fi/onto/mesh/D000001
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