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Concept information

Preferred term

ATP Binding Cassette Transporter, Subfamily G, Member 2  

Type

  • Topical Descriptor

Entry terms

  • ABCG2 Protein
  • ABCG2 Transporter
  • ATP Binding Cassette Transporter, Sub-Family G, Member 2
  • CD338 Antigen

Scope note

  • ATP-binding cassette transporter, sub-family G protein that functions as a high capacity UREA exporter, transporter of STEROLS, and in the absorption and efflux of many drugs. Its efflux activity for ANTINEOPLASTIC AGENTS contributes to DRUG RESISTANCE. It functions as a homodimer and is expressed by cells in a variety of organs, as well as by NEOPLASTIC STEM CELLS.

History note

  • 2019 (2017)

In other languages

URI

http://www.yso.fi/onto/mesh/D000070997

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