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Concept information

Preferred term

Abciximab  

Type

  • Topical Descriptor

Entry terms

  • c7E3 Fab
  • Chimeric 7E3 Fab
  • Fab, Chimeric 7E3

Scope note

  • A Fab fragment of the chimeric monoclonal antibody 7E3 that binds to the glycoprotein IIb-IIIa receptor of human platelets, and blocks PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX, potently inhibiting PLATELET AGGREGATION. It is used in treatment of refractory unstable angina, and for prevention of ischemic complications in patients undergoing percutaneous coronary procedures such as ANGIOPLASTY; ATHERECTOMY; or stenting.

History note

  • 2019 (1994)

In other languages

URI

http://www.yso.fi/onto/mesh/D000077284

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