Concept information
Preferred term
Abciximab
Type
-
Topical Descriptor
Broader concept
Entry terms
- c7E3 Fab
- Chimeric 7E3 Fab
- Fab, Chimeric 7E3
Scope note
- A Fab fragment of the chimeric monoclonal antibody 7E3 that binds to the glycoprotein IIb-IIIa receptor of human platelets, and blocks PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX, potently inhibiting PLATELET AGGREGATION. It is used in treatment of refractory unstable angina, and for prevention of ischemic complications in patients undergoing percutaneous coronary procedures such as ANGIOPLASTY; ATHERECTOMY; or stenting.
History note
- 2019 (1994)
In other languages
-
Finnish
-
Swedish
URI
http://www.yso.fi/onto/mesh/D000077284
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