Finto: MeSH: Alzheimer Disease

Nervous System Diseases > Neurodegenerative Diseases > Tauopathies > Alzheimer Disease

Nervous System Diseases > Central Nervous System Diseases > Brain Diseases > Dementia > Alzheimer Disease

Mental Disorders > Neurocognitive Disorders > Dementia > Alzheimer Disease

Alzheimer Disease

A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)

1998(1963); for DEMENTIA, PRESENILE and DEMENTIA, PRIMARY DEGENERATIVE SENILE use DEMENTIA 1981-1999; for DEMENTIA SENILE use DEMENTIA 1966-1999

http://www.yso.fi/onto/mesh/D000544

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