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Preferred term

Vinca Alkaloids  

Type

  • Topical Descriptor

Scope note

  • A group of indole-indoline dimers which are ALKALOIDS obtained from the VINCA genus of plants. They inhibit polymerization of TUBULIN into MICROTUBULES thus blocking spindle formation and arresting cells in METAPHASE. They are some of the most useful ANTINEOPLASTIC AGENTS.

History note

  • 73

In other languages

URI

http://www.yso.fi/onto/mesh/D014748

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