Concept information
Preferred term
Amyloid beta-Protein Precursor
Type
-
Topical Descriptor
Broader concept
Narrower concepts
Entry terms
- Amyloid A4 Protein Precursor
- Amyloid beta Precursor Protein
- Amyloid Protein Precursor
- beta Amyloid Protein Precursor
- beta-Amyloid Protein Precursor
- Nexin 2, Protease
- Nexin II, Protease
- Protease Nexin 2
- Protease Nexin II
Scope note
- A single-pass type I membrane protein. It is cleaved by AMYLOID PRECURSOR PROTEIN SECRETASES to produce peptides of varying amino acid lengths. A 39-42 amino acid peptide, AMYLOID BETA-PEPTIDES is a principal component of the extracellular amyloid in SENILE PLAQUES.
History note
- 92; was AMYLOID BETA PROTEIN PRECURSOR (NM) 1988-91; AMYLOID A4 PROTEIN PRECURSOR was NM 1987-94
In other languages
-
Finnish
-
amyloidibeetaproteiinin prekursori
-
Swedish
URI
http://www.yso.fi/onto/mesh/D016564
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