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Concept information

Preferred term

Amyloid beta-Protein Precursor  

Type

  • Topical Descriptor

Narrower concepts

Entry terms

  • Amyloid A4 Protein Precursor
  • Amyloid beta Precursor Protein
  • Amyloid Protein Precursor
  • beta Amyloid Protein Precursor
  • beta-Amyloid Protein Precursor
  • Nexin 2, Protease
  • Nexin II, Protease
  • Protease Nexin 2
  • Protease Nexin II

Scope note

  • A single-pass type I membrane protein. It is cleaved by AMYLOID PRECURSOR PROTEIN SECRETASES to produce peptides of varying amino acid lengths. A 39-42 amino acid peptide, AMYLOID BETA-PEPTIDES is a principal component of the extracellular amyloid in SENILE PLAQUES.

History note

  • 92; was AMYLOID BETA PROTEIN PRECURSOR (NM) 1988-91; AMYLOID A4 PROTEIN PRECURSOR was NM 1987-94

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URI

http://www.yso.fi/onto/mesh/D016564

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