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Amino Acids, Peptides, and Proteins > Proteins > Nerve Tissue Proteins > Microtubule-Associated Proteins > tau Proteins
... > Amino Acids, Peptides, and Proteins > Proteins > Cytoskeletal Proteins > Microtubule Proteins > Microtubule-Associated Proteins > tau Proteins
... > Chemical Actions and Uses > Specialty Uses of Chemicals > Biomedical and Dental Materials > Polymers > Biopolymers > Microtubule Proteins > Microtubule-Associated Proteins > tau Proteins
... > Technology, Industry, and Agriculture > Manufactured Materials > Biomedical and Dental Materials > Polymers > Biopolymers > Microtubule Proteins > Microtubule-Associated Proteins > tau Proteins
... > Macromolecular Substances > Polymers > Biopolymers > Microtubule Proteins > Microtubule-Associated Proteins > tau Proteins

Preferred term

tau Proteins  

Type

  • Topical Descriptor

Broader concept

Related concepts

Entry terms

  • Protein, tau
  • tau Protein

Scope note

  • Microtubule-associated proteins that are mainly expressed in neurons. Tau proteins constitute several isoforms and play an important role in the assembly of tubulin monomers into microtubules and in maintaining the cytoskeleton and axonal transport. Aggregation of specific sets of tau proteins in filamentous inclusions is the common feature of intraneuronal and glial fibrillar lesions (NEUROFIBRILLARY TANGLES; NEUROPIL THREADS) in numerous neurodegenerative disorders (ALZHEIMER DISEASE; TAUOPATHIES).

History note

  • 1992; use TAU (NM) 1977-91

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URI

http://www.yso.fi/onto/mesh/D016875

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