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... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptors, Immunologic > Integrins > Receptors, Cytoadhesin > Integrin alpha6beta4
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptors, Immunologic > Receptors, Laminin > Integrin alpha6beta4

Preferred term

Integrin alpha6beta4  

Type

  • Topical Descriptor

Broader concept

Related concepts

Entry terms

  • A9 Antigen
  • alpha(6)beta(4) Epithelial Integrin
  • alpha6 beta4 Integrin
  • alpha(6)beta(4) Integrin
  • Antigen, A9
  • beta4 Integrin, alpha6
  • Integrin, alpha6 beta4
  • Integrin alpha(6),beta(4)
  • Laminin-5 Receptor (alpha6beta4 Integrin)
  • TSP-180
  • Tumor Specific Protein 180 Complex
  • Tumor Specific Protein-180 Complex

Scope note

  • This intrgrin is a key component of HEMIDESMOSOMES and is required for their formation and maintenance in epithelial cells. Integrin alpha6beta4 is also found on thymocytes, fibroblasts, and Schwann cells, where it functions as a laminin receptor (RECEPTORS, LAMININ) and is involved in wound healing, cell migration, and tumor invasiveness.

History note

  • 2003; use INTEGRIN ALPHA6BETA4 (NM) 1988-2002

In other languages

URI

http://www.yso.fi/onto/mesh/D039161

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