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... > Enzymes and Coenzymes > Enzymes > Hydrolases > Esterases > Carboxylic Ester Hydrolases > Phospholipases > Phospholipases A > Phospholipases A2 > Phospholipases A2, Secretory
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Esterases > Phosphoric Diester Hydrolases > Phospholipases > Phospholipases A > Phospholipases A2 > Phospholipases A2, Secretory

Preferred term

Phospholipases A2, Secretory  

Type

  • Topical Descriptor

Broader concept

Narrower concepts

Entry terms

  • A2, Secreted Phospholipase
  • Phospholipase A2, Secreted
  • Phospholipase A2, Secretory
  • Phospholipases A2, Secreted
  • Phospholipases, SPLA2
  • Secreted Phospholipase A2
  • Secreted Phospholipases A2
  • Secretory Phospholipase A2
  • sPLA(2)
  • sPLA2
  • SPLA2 Phospholipases
  • sPLA2s

Note

  • /antag: coordinate with PHOSPHOLIPASE A2 INHIBITORS

Scope note

  • A subcategory of phospholipases A2 that are secreted from cells. They are 14 kDa proteins containing multiple disulfide-bonds and access their substrate via an interfacial binding site that interacts with phospholipid membranes. In addition specific PHOSPHOLIPASE A2 RECEPTORS can bind to and internalize the enzymes.

History note

  • 2008

In other languages

URI

http://www.yso.fi/onto/mesh/D054497

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