Concept information
Preferred term
Aphasia, Primary Progressive
Type
-
Topical Descriptor
Narrower concepts
Entry terms
- Mesulam's Syndrome
- Mesulam Syndrome
- Syndrome, Mesulam
- Syndrome, Mesulam's
Note
- a clinical entity: do not confuse with descriptions of the progression of aphasia in case reports
Scope note
- A progressive form of dementia characterized by the global loss of language abilities and initial preservation of other cognitive functions. Fluent and nonfluent subtypes have been described. Eventually a pattern of global cognitive dysfunction, similar to ALZHEIMER DISEASE, emerges. Pathologically, there are no Alzheimer or PICK DISEASE like changes, however, spongiform changes of cortical layers II and III are present in the TEMPORAL LOBE and FRONTAL LOBE. (From Brain 1998 Jan;121(Pt 1):115-26)
History note
- 1996
In other languages
-
Finnish
-
primaarinen etenevä afasia
-
Swedish
URI
http://www.yso.fi/onto/mesh/D018888
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