Concept information
Preferred term
Alarmins
Type
-
Topical Descriptor
Broader concept
Entry terms
- Alarmin
- Alarmin Proteins
- Damage Associated Molecular Pattern Molecules
- Damage-Associated Molecular Pattern Molecules
- Danger Associated Molecular Pattern Molecules
- Danger-Associated Molecular Pattern Molecules
Scope note
- A structurally diverse group of endogenous molecules that are multifunctional, having physiological functions inside the cell, but when released from dying cells or from cells under stress or certain immune cells, they function to activate INNATE IMMUNITY. Uncontrolled and excessive release of alarmins may contribute to INFLAMMATION; CARCINOGENESIS, and NEOPLASM METASTASIS. Alarmins are also critical for heart and nerve tissue homeostasis.
History note
- 2016
In other languages
-
Finnish
-
Swedish
-
Alarmin
URI
http://www.yso.fi/onto/mesh/D000067531
{{label}}
{{#each values }} {{! loop through ConceptPropertyValue objects }}
{{#if prefLabel }}
{{/if}}
{{/each}}
{{#if notation }}{{ notation }} {{/if}}{{ prefLabel }}
{{#ifDifferentLabelLang lang }} ({{ lang }}){{/ifDifferentLabelLang}}
{{#if vocabName }}
{{ vocabName }}
{{/if}}