Concept information
Preferred term
ELAV-Like Protein 1
Type
-
Topical Descriptor
Broader concept
Entry terms
- Antigen, HuR
- ELAVL1 protein
- HuR Antigen
- HuR Paraneoplastic Encephalomyelitis Antigen
- HuR Protein
- protein, ELAVL1
- Protein, HuR
Scope note
- An RRM protein that binds to the 3'-UTR region of mRNAs and increases their stability. In EMBRYONIC STEM CELLS, it binds to poly-U elements and AU-rich elements (AREs) in the 3'-UTR of target mRNAs and preferentially binds mRNAs that are not methylated by N6-methyladenosine (m6A), to stabilize them and promote differentiation.
History note
- 2016; use ELAV PROTEINS 2012-2015
In other languages
-
Finnish
-
Swedish
-
ELAVL1 protein
-
HuR antigen
-
HuR protein
URI
http://www.yso.fi/onto/mesh/D000067780
{{label}}
{{#each values }} {{! loop through ConceptPropertyValue objects }}
{{#if prefLabel }}
{{/if}}
{{/each}}
{{#if notation }}{{ notation }} {{/if}}{{ prefLabel }}
{{#ifDifferentLabelLang lang }} ({{ lang }}){{/ifDifferentLabelLang}}
{{#if vocabName }}
{{ vocabName }}
{{/if}}