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... > Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > RNA-Binding Proteins > RNA Recognition Motif Proteins > CELF Proteins > CELF1 Protein
... > Amino Acids, Peptides, and Proteins > Proteins > Nucleoproteins > RNA-Binding Proteins > RNA Recognition Motif Proteins > CELF Proteins > CELF1 Protein

Preferred term

CELF1 Protein  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • 2 Protein, Bruno-Like
  • BRUNOL2 Protein
  • Bruno Like 2 Protein
  • Bruno-Like 2 Protein
  • CUGBP1 Protein
  • CUGBP, Elav Like Family Member 1 Protein
  • CUGBP, Elav-Like Family Member 1 Protein
  • CUG Triplet Repeat, RNA Binding Protein 1
  • CUG Triplet Repeat, RNA-Binding Protein 1
  • Protein, BRUNOL2
  • Protein, Bruno-Like 2
  • Protein, CUGBP1

Scope note

  • A member of the CELF PROTEINS family which binds GU rich elements (GREs) and CUG-triplet repeats in the 3'UTR of mammalian mRNA transcripts that undergo rapid turnover. It also binds AU-rich elements (AREs or EDEN-like) in the 3'UTR of JUN and FOS mRNAs. Mutations in the human CELF1 gene are associated with MYOTONIC DYSTROPHY type 1.

History note

  • 2016

In other languages

URI

http://www.yso.fi/onto/mesh/D000067879

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