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Concept information

... > Polycyclic Compounds > Macrocyclic Compounds > Polyketides > Macrolides > Sirolimus > Everolimus
... > Organic Chemicals > Lactones > Polyketides > Macrolides > Sirolimus > Everolimus

Preferred term

Everolimus  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • 40-O-(2-hydroxyethyl)-rapamycin
  • RAD, SDZ
  • SDZ RAD
  • SDZ-RAD

Scope note

  • A derivative of sirolimus and an inhibitor of TOR SERINE-THREONINE KINASES. It is used to prevent GRAFT REJECTION in heart and kidney transplant patients by blocking cell proliferation signals. It is also an ANTINEOPLASTIC AGENT.

History note

  • 2016 (1997)

In other languages

URI

http://www.yso.fi/onto/mesh/D000068338

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