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Concept information

Preferred term

Omalizumab  

Type

  • Topical Descriptor

Entry terms

  • Xolair

Scope note

  • An anti-IgE, recombinant, humanized monoclonal antibody which specifically binds to the C epsilon3 domain of IMMUNOGLOBULIN E, the site of high-affinity IgE receptor binding. It inhibits the binding of IgE to MAST CELLS and BASOPHILS to reduce the severity of the allergic response and is used in the management of persistent allergic ASTHMA.

History note

  • 2016 (2001)

In other languages

URI

http://www.yso.fi/onto/mesh/D000069444

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