Skip to main content

Medical Subject Headings

Search from vocabulary

Content language

Concept information

Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > NLR Proteins
Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > NLR Proteins

Preferred term

NLR Proteins  

Type

  • Topical Descriptor

Broader concept

Narrower concepts

Entry terms

  • NLR Protein
  • NOD like Receptor
  • NOD-like Receptor
  • NOD like Receptors
  • NOD-like Receptors
  • Nucleotide Binding Domain Leucine Rich Repeat Protein
  • Nucleotide-Binding Domain Leucine-Rich Repeat Protein
  • Nucleotide binding Domain Leucine rich Repeat Proteins
  • Nucleotide-binding Domain Leucine-rich Repeat Proteins
  • Protein, NLR
  • Receptor, NOD-like
  • Receptors, NOD-like

Scope note

  • Intracellular signaling proteins that are defined by the presence of a NUCLEOTIDE-binding region and LEUCINE-rich repeats. Their general structure consists of any of a variety of effector domains at their N-termini such as a caspase recruitment domain (CARD), a central nucleotide-binding domain, and a variable number of C-terminal leucine-rich repeats. They are important for pathogen recognition in the INNATE IMMUNE RESPONSE of animals and plants. Members of the NLR protein family include the NOD SIGNALING ADAPTOR PROTEINS.

History note

  • 2017

In other languages

URI

http://www.yso.fi/onto/mesh/D000070576

Download this concept:

RDF/XML TURTLE JSON-LD Created 7/8/16, last modified 5/27/20