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... > Chemical Phenomena > Biochemical Phenomena > Molecular Structure > Molecular Conformation > Protein Conformation > Protein Structural Elements > Protein Domains > Methyl CpG Binding Domain
... > Chemical Phenomena > Biochemical Phenomena > Molecular Structure > Molecular Conformation > Protein Conformation > Protein Structure, Tertiary > Protein Domains > Methyl CpG Binding Domain

Preferred term

Methyl CpG Binding Domain  

Type

  • Topical Descriptor

Broader concept

Related concepts

Entry terms

  • Methyl CpG DNA Binding Domain

Scope note

  • A protein domain of about 70 amino acids in length that folds into a sandwich structure consisting of a beta sheet, alpha helix, and C-terminal hairpin loop which forms a hydrophobic methylated-DNA binding patch. It binds to methylated CPG ISLANDS in eukaryotes and occurs with other DNA and CHROMATIN binding domains such as AT-HOOK MOTIFS in eukaryotic DNA BINDING PROTEINS.

History note

  • 2017

In other languages

URI

http://www.yso.fi/onto/mesh/D000070593

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