Concept information
Preferred term
Perilipin-1
Type
-
Topical Descriptor
Broader concept
Entry terms
- Perilipin
- Perilipin A Protein
- Perilipin B Protein
- Perilipin Protein
- PERI Protein
- Plin Protein
- Protein, PERI
- Protein, Perilipin
- Protein, Perilipin A
- Protein, Perilipin B
- Protein, Plin
Scope note
- A lipid droplet protein that is expressed primarily by ADIPOCYTES of WHITE ADIPOSE TISSUE and BROWN ADIPOSE TISSUE. It co-localizes with MACROPHAGES and FOAM CELLS of artherosclerotic lesions and stabilizes LIPID DROPLETS by inhibiting HORMONE SENSITIVE LIPASE. It may also protect TRIGLYCERIDES against hydrolysis within the PLASMA MEMBRANE and modulate CHOLESTEROL ESTER HYDROLASE activity.
History note
- 2017 (1991)
In other languages
-
Finnish
-
PERI-protein
Swedish
-
Perilipinprotein
URI
http://www.yso.fi/onto/mesh/D000070778
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