Concept information
Preferred term
Perilipin-3
Type
-
Topical Descriptor
Broader concept
Entry terms
- 47 kDa Mannose 6 Phosphate Receptor Binding Protein
- 47 kDa Mannose 6-Phosphate Receptor-Binding Protein
- 47 kDa MPR binding Protein
- 47 kDa MPR-binding Protein
- Cargo Selection Protein TIP47
- Mannose 6 Phosphate Receptor Binding Protein 1
- Mannose-6-Phosphate Receptor-Binding Protein 1
- Perilipin 3 Protein
- Placental Protein 17
- PLIN3 Protein
- Protein, Perilipin 3
- Protein, PLIN3
- Protein, TIP47
- Tail Interacting Protein of 47 kDa
- TIP47 Protein
Scope note
- A perilipin that localizes to LIPID DROPLETS; CYTOPLASM; ENDOSOMES; and PLASMA MEMBRANE, especially in MACROPHAGES. It functions as a transporter of free fatty acids to lipid droplets to promote their biogenesis and growth. It is also required for the transport of the MANNOSE-6-PHOSPHATE RECEPTOR from endosomes to the TRANS-GOLGI NETWORK. Its structure consists of four helix bundles that interact with the hydrophobic lipid droplet surface.
History note
- 2017 (1983)
In other languages
-
Finnish
-
Swedish
-
Perilipin-3-protein
-
PLIN3 protein
URI
http://www.yso.fi/onto/mesh/D000070796
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