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Concept information

Preferred term

Perilipin-3  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • 47 kDa Mannose 6 Phosphate Receptor Binding Protein
  • 47 kDa Mannose 6-Phosphate Receptor-Binding Protein
  • 47 kDa MPR binding Protein
  • 47 kDa MPR-binding Protein
  • Cargo Selection Protein TIP47
  • Mannose 6 Phosphate Receptor Binding Protein 1
  • Mannose-6-Phosphate Receptor-Binding Protein 1
  • Perilipin 3 Protein
  • Placental Protein 17
  • PLIN3 Protein
  • Protein, Perilipin 3
  • Protein, PLIN3
  • Protein, TIP47
  • Tail Interacting Protein of 47 kDa
  • TIP47 Protein

Scope note

  • A perilipin that localizes to LIPID DROPLETS; CYTOPLASM; ENDOSOMES; and PLASMA MEMBRANE, especially in MACROPHAGES. It functions as a transporter of free fatty acids to lipid droplets to promote their biogenesis and growth. It is also required for the transport of the MANNOSE-6-PHOSPHATE RECEPTOR from endosomes to the TRANS-GOLGI NETWORK. Its structure consists of four helix bundles that interact with the hydrophobic lipid droplet surface.

History note

  • 2017 (1983)

In other languages

URI

http://www.yso.fi/onto/mesh/D000070796

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