Concept information
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Proteins
Intracellular Signaling Peptides and Proteins
Protein-Tyrosine Kinases
Receptor Protein-Tyrosine Kinases
...
Peptides
Intracellular Signaling Peptides and Proteins
Protein-Tyrosine Kinases
Receptor Protein-Tyrosine Kinases
Preferred term
Discoidin Domain Receptors
Type
-
Topical Descriptor
Broader concept
Narrower concepts
Entry terms
- DDR Proteins
- Discoidin Domain Receptor
- Proteins, DDR
- Receptor, Discoidin Domain
Scope note
- Receptor tyrosine kinases that bind COLLAGENS. They are characterized by the presence of extracellular DISCOIDIN DOMAINS that activate SIGNAL TRANSDUCTION PATHWAYS in response to collagen binding. They may also be cleaved by MATRIX METALLOPROTEINASES to mediate cell interactions with the EXTRACELLULAR MATRIX.
History note
- 2017 (1999)
In other languages
-
Finnish
URI
http://www.yso.fi/onto/mesh/D000070818
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