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Concept information

Preferred term

Discoidin Domain Receptors  

Type

  • Topical Descriptor

Entry terms

  • DDR Proteins
  • Discoidin Domain Receptor
  • Proteins, DDR
  • Receptor, Discoidin Domain

Scope note

  • Receptor tyrosine kinases that bind COLLAGENS. They are characterized by the presence of extracellular DISCOIDIN DOMAINS that activate SIGNAL TRANSDUCTION PATHWAYS in response to collagen binding. They may also be cleaved by MATRIX METALLOPROTEINASES to mediate cell interactions with the EXTRACELLULAR MATRIX.

History note

  • 2017 (1999)

In other languages

URI

http://www.yso.fi/onto/mesh/D000070818

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