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Amino Acids, Peptides, and Proteins > Proteins > Cytoskeletal Proteins > Microfilament Proteins > Tensins
... > Chemical Actions and Uses > Specialty Uses of Chemicals > Biomedical and Dental Materials > Polymers > Biopolymers > Microfilament Proteins > Tensins
... > Technology, Industry, and Agriculture > Manufactured Materials > Biomedical and Dental Materials > Polymers > Biopolymers > Microfilament Proteins > Tensins
Macromolecular Substances > Polymers > Biopolymers > Microfilament Proteins > Tensins

Preferred term

Tensins  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Tensin

Scope note

  • A family of multidomain microfilament proteins that bind ACTIN FILAMENTS and INTEGRINS at FOCAL ADHESIONS. They generally consist of an N-terminal domain with homology to PHOSPHOTYROSINE PHOSPHATASE, a C2 DOMAIN; unique central regions rich in PROLINE; ALANINE; GLYCINE; and SERINE; an SH2 DOMAIN; and a C-terminal phosphotyrosine-binding region. They are involved in CELL MIGRATION; CELL ADHESION; SIGNAL TRANSDUCTION; and reorganization of the CYTOSKELETON.

History note

  • 2017 (1992)

In other languages

URI

http://www.yso.fi/onto/mesh/D000070876

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