Concept information
Preferred term
Mismatch Repair Endonuclease PMS2
Type
-
Topical Descriptor
Broader concept
Entry terms
- PMS1 Homolog 2, Mismatch Repair Protein
- PMS 2 Protein
- PMS-2 Protein
- PMS2 Protein
- Postmeiotic Segregation Increased S. cerevisiae 2
- Postmeiotic Segregation Increased-S. cerevisiae-2
Scope note
- A MutL protein and component of the DNA MISMATCH REPAIR system. Its ENDONUCLEASE activity introduces SINGLE-STRAND DNA BREAKS which create entry points for EXO1 exonuclease to remove the strand containing the mismatch. It may also function in DNA DAMAGE signaling.
History note
- 2017
In other languages
URI
http://www.yso.fi/onto/mesh/D000070976
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