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Concept information

Preferred term

Mismatch Repair Endonuclease PMS2  

Type

  • Topical Descriptor

Entry terms

  • PMS1 Homolog 2, Mismatch Repair Protein
  • PMS 2 Protein
  • PMS-2 Protein
  • PMS2 Protein
  • Postmeiotic Segregation Increased S. cerevisiae 2
  • Postmeiotic Segregation Increased-S. cerevisiae-2

Scope note

  • A MutL protein and component of the DNA MISMATCH REPAIR system. Its ENDONUCLEASE activity introduces SINGLE-STRAND DNA BREAKS which create entry points for EXO1 exonuclease to remove the strand containing the mismatch. It may also function in DNA DAMAGE signaling.

History note

  • 2017

In other languages

URI

http://www.yso.fi/onto/mesh/D000070976

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