Concept information
...
Glycoproteins
Membrane Glycoproteins
ATP-Binding Cassette Transporters
ATP Binding Cassette Transporter, Subfamily G
...
Glycoproteins
Membrane Glycoproteins
ATP-Binding Cassette Transporters
ATP Binding Cassette Transporter, Subfamily G
...
Membrane Proteins
Membrane Glycoproteins
ATP-Binding Cassette Transporters
ATP Binding Cassette Transporter, Subfamily G
Preferred term
ATP Binding Cassette Transporter, Subfamily G, Member 2
Type
-
Topical Descriptor
Broader concept
Entry terms
- ABCG2 Protein
- ABCG2 Transporter
- ATP Binding Cassette Transporter, Sub-Family G, Member 2
- CD338 Antigen
Scope note
- ATP-binding cassette transporter, sub-family G protein that functions as a high capacity UREA exporter, transporter of STEROLS, and in the absorption and efflux of many drugs. Its efflux activity for ANTINEOPLASTIC AGENTS contributes to DRUG RESISTANCE. It functions as a homodimer and is expressed by cells in a variety of organs, as well as by NEOPLASTIC STEM CELLS.
History note
- 2019 (2017)
In other languages
-
Finnish
-
ATP:tä sitova kasettikuljettimen alaperhe G:n jäsen 2
URI
http://www.yso.fi/onto/mesh/D000070997
{{label}}
{{#each values }} {{! loop through ConceptPropertyValue objects }}
{{#if prefLabel }}
{{/if}}
{{/each}}
{{#if notation }}{{ notation }} {{/if}}{{ prefLabel }}
{{#ifDifferentLabelLang lang }} ({{ lang }}){{/ifDifferentLabelLang}}
{{#if vocabName }}
{{ vocabName }}
{{/if}}