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Concept information

Preferred term

Endoglin  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Antigen, CD105
  • CD105 Antigen
  • Endoglin Protein

Scope note

  • A membrane glycoprotein and ANGIOGENESIS FACTOR that is expressed by cells of the VASCULAR ENDOTHELIUM; VASCULAR SMOOTH MUSCLE; and MONOCYTES. It functions as a co-receptor for TRANSFORMING GROWTH FACTOR BETA and modulates CELL ADHESION. Mutations in the endoglin gene are associated with cases of HEREDITARY HEMORRHAGIC TELANGIECTASIA.

History note

  • 2017

In other languages

URI

http://www.yso.fi/onto/mesh/D000071063

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