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Concept information

Preferred term

ADAMTS5 Protein  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • ADAMTS11 Protein
  • ADAMTS5 Protease
  • ADAMTS 5 Protein
  • ADAMTS-5 Protein
  • A Disintegrin And Metalloproteinase With Thrombospondin Motifs 5 Protein
  • Aggrecanase 2
  • Aggrecanase-2

Scope note

  • An ADAMTS protease that contains two C-terminal thrombospondin (TS) motifs. It functions primarily as an aggrecanase, cleaving AGGRECAN in CARTILAGE, and may be involved in the destruction of aggrecan in ARTHRITIS.

History note

  • 2017

In other languages

URI

http://www.yso.fi/onto/mesh/D000071116

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