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... > Amino Acids, Peptides, and Proteins > Proteins > Scleroproteins > Extracellular Matrix Proteins > ADAMTS Proteins > ADAMTS4 Protein
... > Amino Acids, Peptides, and Proteins > Proteins > Glycoproteins > ADAM Proteins > ADAMTS Proteins > ADAMTS4 Protein
... > Carbohydrates > Glycoconjugates > Glycoproteins > ADAM Proteins > ADAMTS Proteins > ADAMTS4 Protein
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Peptide Hydrolases > Endopeptidases > Metalloendopeptidases > ADAM Proteins > ADAMTS Proteins > ADAMTS4 Protein
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Peptide Hydrolases > Metalloproteases > Metalloendopeptidases > ADAM Proteins > ADAMTS Proteins > ADAMTS4 Protein

Preferred term

ADAMTS4 Protein  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • ADAMTS 4 Protein
  • ADAMTS-4 Protein
  • A Disintegrin And Metalloproteinase With Thrombospondin Motifs 4 Protein
  • Aggrecanase 1
  • Aggrecanase-1

Scope note

  • An ADAMTS protease similar to ADAMTS5 PROTEIN. It contains a single C-terminal thrombospondin (TS) motif and cleaves AGGRECAN in CARTILAGE. It may also be involved in the destruction of aggrecan in ARTHRITIS.

History note

  • 2017 (1999)

In other languages

URI

http://www.yso.fi/onto/mesh/D000071121

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RDF/XML TURTLE JSON-LD Created 7/6/16, last modified 2/26/16