Concept information
Preferred term
Promyelocytic Leukemia Protein
Type
-
Topical Descriptor
Broader concept
Entry terms
- RNF71 Protein
- TRIM19 Protein
Scope note
- A tripartite motif protein that contains three ZINC FINGERS, including a RING FINGER DOMAIN, at its N-terminal. Several nuclear and one cytoplasmic isoforms result from alternative splicing of the PML gene; most nuclear isoforms localize to subnuclear structures (PML nuclear bodies) that are disrupted in ACUTE PROMYELOCYTIC LEUKEMIA cells.
History note
- 2017
In other languages
-
Finnish
-
promyelosyyttileukemiaproteiini
-
Swedish
-
RNF71 protein
-
TRIM19 protein
URI
http://www.yso.fi/onto/mesh/D000071156
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