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Concept information

Preferred term

Promyelocytic Leukemia Protein  

Type

  • Topical Descriptor

Entry terms

  • RNF71 Protein
  • TRIM19 Protein

Scope note

  • A tripartite motif protein that contains three ZINC FINGERS, including a RING FINGER DOMAIN, at its N-terminal. Several nuclear and one cytoplasmic isoforms result from alternative splicing of the PML gene; most nuclear isoforms localize to subnuclear structures (PML nuclear bodies) that are disrupted in ACUTE PROMYELOCYTIC LEUKEMIA cells.

History note

  • 2017

In other languages

URI

http://www.yso.fi/onto/mesh/D000071156

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