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Amino Acids, Peptides, and Proteins > Peptides > Trefoil Factors

Preferred term

Trefoil Factors  

Type

  • Topical Descriptor

Broader concept

Narrower concepts

Entry terms

  • Factor, Trefoil
  • Peptide, TFF
  • Peptide, Trefoil
  • Protein, Trefoil
  • TFF Peptide
  • TFF Peptides
  • Trefoil Factor
  • Trefoil Factor Family Peptides
  • Trefoil Factor Family Proteins
  • Trefoil Peptide
  • Trefoil Peptides
  • Trefoil Protein
  • Trefoil Proteins

Scope note

  • A family of small peptides expressed primarily by MUCOUS MEMBRANE EPITHELIAL CELLS in vertebrates. Their structure is highly conserved and is defined by a three-leaved (trefoil) domain of 42 or 43 amino acids; it includes six cysteines that create the trefoil structure through disulfide bridges. Trefoil peptides may form dimers with each other, or associate with MUCINS and other factors. They are important for maintaining epithelial integrity and for protection from noxious agents.

History note

  • 2017

In other languages

URI

http://www.yso.fi/onto/mesh/D000071162

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