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Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Membrane Glycoproteins > Signaling Lymphocytic Activation Molecule Family
Carbohydrates > Glycoconjugates > Glycoproteins > Membrane Glycoproteins > Signaling Lymphocytic Activation Molecule Family
Amino Acids, Peptides, and Proteins > Proteins > Glycoproteins > Membrane Glycoproteins > Signaling Lymphocytic Activation Molecule Family
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptors, Immunologic > Signaling Lymphocytic Activation Molecule Family

Preferred term

Signaling Lymphocytic Activation Molecule Family  

Type

  • Topical Descriptor

Broader concept

Narrower concepts

Entry terms

  • Signaling Lymphocytic Activation Molecule Family Receptors
  • Signaling Lymphocytic Activation Molecule Receptors
  • Signaling Lymphocytic Activation Molecules
  • SLAM Family Receptors
  • SLAMF Receptors

Scope note

  • Type-I membrane glycoproteins that are expressed primarily on the surface of CD4 or CD8-positive T-CELLS; NATURAL KILLER CELLS; and some populations of B CELLS. They are characterized by an N-terminal, extracellular IMMUNOGLOBULIN-LIKE DOMAIN and a membrane-proximal IMMUNOGLOBULIN C2-SET DOMAIN. SLAMF receptors typically signal through homophilic interactions and are important for mediating the immune response and immune cell differentiation.

History note

  • 2017

In other languages

URI

http://www.yso.fi/onto/mesh/D000071176

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