Concept information
Preferred term
Pharmacogenomic Variants
Type
-
Topical Descriptor
Broader concept
Entry terms
- Genetic Variant, Pharmacokinetic
- Genetic Variants, Pharmacokinetic
- Pharmacogenetic Variant
- Pharmacogenetic Variants
- Pharmacokinetic Genetic Variant
- Pharmacokinetic Genetic Variants
- Variant, Pharmacogenetic
- Variants, Pharmacogenetic
Scope note
- Naturally occurring genetic variations associated with drug response (e.g., dosage, extent and rate of metabolic processes). While these variants are not markers for GENETIC PREDISPOSITION TO DISEASE they influence PHARMACOKINETICS and pharmacodynamics and often occur on genes encoding drug metabolism enzymes and transporters (e.g., ANGIOTENSIN CONVERTING ENZYME; CYTOCHROME P-450 CYP2D6).
History note
- 2017
In other languages
-
Finnish
-
farmakogeneettiset eroavaisuudet
-
farmakogeneettiset muodot
-
Swedish
-
Farmakogenomiska varianter
URI
http://www.yso.fi/onto/mesh/D000071184
{{label}}
{{#each values }} {{! loop through ConceptPropertyValue objects }}
{{#if prefLabel }}
{{/if}}
{{/each}}
{{#if notation }}{{ notation }} {{/if}}{{ prefLabel }}
{{#ifDifferentLabelLang lang }} ({{ lang }}){{/ifDifferentLabelLang}}
{{#if vocabName }}
{{ vocabName }}
{{/if}}