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Amino Acids, Peptides, and Proteins > Proteins > Autophagy-Related Proteins > Beclin-1
Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Apoptosis Regulatory Proteins > Beclin-1
Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Apoptosis Regulatory Proteins > Beclin-1

Preferred term

Beclin-1  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • ATG 6 Protein
  • ATG-6 Protein
  • ATG6 Protein
  • Beclin1
  • Beclin 1 Protein
  • Beclin-1 Protein
  • Coiled coil Myosin like Bcl2 interacting Protein
  • Coiled-coil Myosin-like Bcl2-interacting Protein
  • GT197 Protein

Scope note

  • An autophagy related protein which functions as a core subunit of PHOSPHATIDYLINOSITOL 3-KINASE MULTIPROTEIN COMPLEXES. It mediates the formation of phosphatidylinositol 3-phosphate and functions in AUTOPHAGY, where it is required for maturation of the AUTOPHAGOSOME. It also functions in ENDOCYTOSIS and CYTOKINESIS as part of a separate complex. Beclin-1 associates with INTRACELLULAR MEMBRANES and interacts with the PROTO-ONCOGENE PROTEINS C-BCL-2 and BCL-X PROTEIN.

History note

  • 2017

In other languages

URI

http://www.yso.fi/onto/mesh/D000071186

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