Concept information
Preferred term
Autophagy-Related Protein 5
Type
-
Topical Descriptor
Broader concept
Entry terms
- Apoptosis Specific Protein
- Apoptosis-Specific Protein
- ATG 5 Protein
- ATG-5 Protein
- ATG5 Protein
- Autophagy Protein 5
- Autophagy Protein-5
- Autophagy Related 5 Protein
- Autophagy-Related 5 Protein
Scope note
- An autophagy-related protein that functions in AUTOPHAGOSOME biogenesis. It is conjugated to the ATG12 PROTEIN via a process that is similar to UBIQUITINATION and involves the ATG7 PROTEIN and ATG10 enzyme. The ATG12-ATG5 conjugate acts as an E3 UBIQUITIN LIGASE-like enzyme and is required for the localization of ATG8 PROTEINS to AUTOPHAGOSOME vesicle membranes and modification of membrane lipids.
History note
- 2017
In other languages
-
Finnish
-
Swedish
-
ATG5 protein
URI
http://www.yso.fi/onto/mesh/D000071187
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