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Concept information

Preferred term

Autophagy-Related Protein 5  

Type

  • Topical Descriptor

Entry terms

  • Apoptosis Specific Protein
  • Apoptosis-Specific Protein
  • ATG 5 Protein
  • ATG-5 Protein
  • ATG5 Protein
  • Autophagy Protein 5
  • Autophagy Protein-5
  • Autophagy Related 5 Protein
  • Autophagy-Related 5 Protein

Scope note

  • An autophagy-related protein that functions in AUTOPHAGOSOME biogenesis. It is conjugated to the ATG12 PROTEIN via a process that is similar to UBIQUITINATION and involves the ATG7 PROTEIN and ATG10 enzyme. The ATG12-ATG5 conjugate acts as an E3 UBIQUITIN LIGASE-like enzyme and is required for the localization of ATG8 PROTEINS to AUTOPHAGOSOME vesicle membranes and modification of membrane lipids.

History note

  • 2017

In other languages

URI

http://www.yso.fi/onto/mesh/D000071187

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