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Amino Acids, Peptides, and Proteins > Proteins > Autophagy-Related Proteins > Autophagy-Related Protein-1 Homolog
Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Protein Serine-Threonine Kinases > Autophagy-Related Protein-1 Homolog
Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Protein Serine-Threonine Kinases > Autophagy-Related Protein-1 Homolog
... > Enzymes and Coenzymes > Enzymes > Transferases > Phosphotransferases > Phosphotransferases (Alcohol Group Acceptor) > Protein Kinases > Protein Serine-Threonine Kinases > Autophagy-Related Protein-1 Homolog

Preferred term

Autophagy-Related Protein-1 Homolog  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Serine Threonine Protein Kinase ULK1
  • Serine-Threonine Protein Kinase ULK1
  • ULK1 Protein
  • Unc 51 Like Autophagy Activating Kinase 1
  • Unc-51 Like Autophagy Activating Kinase 1
  • Unc 51 Like Kinase 1
  • Unc-51-Like Kinase 1

Scope note

  • A serine/threonine-protein kinase that functions in AUTOPHAGY in response to starvation. It acts on the PHOSPHATIDYLINOSITOL 3-KINASE complex PIK3C3 to regulate AUTOPHAGOSOME formation. It also functions as both a downstream effector and negative regulator of mammalian target of rapamycin complex 1 (mTORC1) and is activated by AMPK, which it also negatively regulates.

History note

  • 2017

In other languages

URI

http://www.yso.fi/onto/mesh/D000071189

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