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Amino Acids, Peptides, and Proteins > Proteins > Autophagy-Related Proteins > Autophagy-Related Protein 12
Amino Acids, Peptides, and Proteins > Proteins > Ubiquitins > Autophagy-Related Protein 12

Preferred term

Autophagy-Related Protein 12  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • ATG12 Protein
  • ATG12, Ubiquitin-Like Protein
  • Ubiquitin Like Protein ATG12
  • Ubiquitin-Like Protein ATG12

Scope note

  • A UBIQUITIN-like modifier protein that functions in AUTOPHAGOSOME formation, CYTOPLASM to VACUOLE transport, MITOPHAGY, and nucleophagy. Conjugation with ATG5 PROTEIN or ATG10 is essential for its function. The ATG12-ATG5 conjugate acts as an E3 UBIQUITIN LIGASE-like enzyme for lipid modification of ATG8 FAMILY PROTEINS and their localization to vesicle membranes.

History note

  • 2017

In other languages

URI

http://www.yso.fi/onto/mesh/D000071192

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RDF/XML TURTLE JSON-LD Created 7/8/16, last modified 2/25/16