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Amino Acids, Peptides, and Proteins > Proteins > Autophagy-Related Proteins > Autophagy-Related Protein 7

Preferred term

Autophagy-Related Protein 7  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • ATG12 Activating Enzyme E1 ATG7
  • ATG12-Activating Enzyme E1 ATG7
  • ATG7 Protein
  • Ubiquitin Activating Enzyme E1 like Protein
  • Ubiquitin-Activating Enzyme E1-like Protein
  • Ubiquitin Like Modifier Activating Enzyme ATG7
  • Ubiquitin-Like Modifier-Activating Enzyme ATG7

Scope note

  • An autophagy related protein that is similar to UBIQUITIN-ACTIVATING ENZYME E1. It functions in CYTOPLASM to VACUOLE transport (Cvt) and AUTOPHAGY by activating ATG12 PROTEIN for its conjugation with ATG5 PROTEIN, as well as the conjugation of ATG8 FAMILY PROTEINS with phosphatidylethanolamine for ATG8 association to Cvt vesicles and AUTOPHAGOSOME membranes. It is also required for the nitrogen starvation response in yeast, MITOPHAGY; and autophagic cell death induced by CASPASE 8 inhibition.

History note

  • 2017

In other languages

URI

http://www.yso.fi/onto/mesh/D000071193

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RDF/XML TURTLE JSON-LD Created 7/8/16, last modified 2/25/16