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... > Chemical Phenomena > Biochemical Phenomena > Molecular Structure > Molecular Conformation > Protein Conformation > Protein Structural Elements > Protein Domains > Protein Interaction Domains and Motifs > Death Domain Superfamily > Pyrin Domain
... > Chemical Phenomena > Biochemical Phenomena > Molecular Structure > Molecular Conformation > Protein Conformation > Protein Structure, Tertiary > Protein Domains > Protein Interaction Domains and Motifs > Death Domain Superfamily > Pyrin Domain

Preferred term

Pyrin Domain  

Type

  • Topical Descriptor

Broader concept

Related concepts

Entry terms

  • DAPIN Domain
  • DAPIN Domains
  • PAAD DAPIN PYRIN Domain
  • PAAD-DAPIN-PYRIN Domain
  • PAAD-DAPIN-PYRIN Domains
  • PADD Domain
  • PADD Domains
  • PYD Domain
  • PYD Domains

Scope note

  • A protein interaction domain of the death domain superfamily. It is characterized by a 6-helix bundle similar to those that occur in DEATH DOMAIN RECEPTORS. Pyrin domains are present in a variety of proteins, especially those that function in INFLAMMASOMES; AUTOPHAGY; and APOPTOSIS. They form homodimers or heterodimers with death domain proteins to facilitate the assembly of signaling complexes.

History note

  • 2017

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URI

http://www.yso.fi/onto/mesh/D000071196

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