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Concept information

Preferred term

Transcriptional Regulator ERG  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Transforming Protein ERG
  • V Ets Avian Erythroblastosis Virus E26 Oncogene Homolog Protein
  • V-Ets Avian Erythroblastosis Virus E26 Oncogene Homolog Protein
  • V Ets Avian Erythroblastosis Virus E26 Oncogene Related Protein
  • V-Ets Avian Erythroblastosis Virus E26 Oncogene Related Protein

Scope note

  • A trans-activator and member of the erythroblast transformation-specific family of transcriptions factors that contain a characteristic ETS MOTIF. It is required for PLATELET CELL ADHESION to the subendothelium and associates with CHIMERIC ONCOGENE PROTEINS in PROSTATE CANCER; EWING'S SARCOMA; and ACUTE MYELOID LEUKEMIA.

History note

  • 2017

In other languages

URI

http://www.yso.fi/onto/mesh/D000071230

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