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... > Amino Acids, Peptides, and Proteins > Proteins > Transcription Factors > Winged-Helix Transcription Factors > Forkhead Transcription Factors > Forkhead Box Protein O3
... > Amino Acids, Peptides, and Proteins > Proteins > DNA-Binding Proteins > Winged-Helix Transcription Factors > Forkhead Transcription Factors > Forkhead Box Protein O3

Preferred term

Forkhead Box Protein O3  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Forkhead in Rhabdomyosarcoma Like 1 Protein
  • Forkhead in Rhabdomyosarcoma-Like 1 Protein
  • FOXO3 Protein
  • Protein, FOXO3

Scope note

  • A forkhead box transcription factor and transcriptional activator which triggers type 1 programmed cell death (APOPTOSIS) in the absence of APOPTOSIS INHIBITING PROTEINS, including neuronal cell death induced by OXIDATIVE STRESS. It recognizes and binds to the DNA sequence 5'-(AG)TAAA(TC)A-3' and also functions in post-transcriptional regulation of the c-MYC PROTO-ONCOGENE.

History note

  • 2017

In other languages

URI

http://www.yso.fi/onto/mesh/D000071316

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