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... > Enzymes and Coenzymes > Enzymes > Hydrolases > Peptide Hydrolases > Endopeptidases > Serine Endopeptidases > Proprotein Convertase 9
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Peptide Hydrolases > Serine Proteases > Serine Endopeptidases > Proprotein Convertase 9
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Peptide Hydrolases > Proprotein Convertases > Proprotein Convertase 9

Preferred term

Proprotein Convertase 9  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • NARC 1 Protein
  • NARC-1 Protein
  • Neural Apoptosis Regulated Convertase 1
  • Neural Apoptosis-Regulated Convertase 1
  • Proprotein Convertase, Subtilisin Kexin Type 9
  • Proprotein Convertase, Subtilisin-Kexin Type 9

Scope note

  • A proprotein convertase that is essential for CHOLESTEROL homeostasis. It binds to and is required for the lysosomal degradation of the LDL RECEPTOR (LDLR); the VLDL receptor, and the APOLIPOPROTEIN E RECEPTOR. It also regulates neuronal APOPTOSIS.

History note

  • 2017

In other languages

URI

http://www.yso.fi/onto/mesh/D000071449

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