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Concept information

Preferred term

Death Domain Superfamily  

Type

  • Topical Descriptor

Entry terms

  • Death Like Domain
  • Death-Like Domain
  • Death Like Domains
  • Death-Like Domains

Scope note

  • A family of structurally-related protein interaction domains characterized by 6-helical closed bundle fold, with Greek key topology and an internal pseudo two-fold symmetry. Death-like domains occur in many proteins that are essential for APOPTOSIS, including CASPASE RECRUITMENT DOMAIN CONTAINING PROTEINS and DEATH DOMAIN RECEPTORS.

History note

  • 2017

In other languages

URI

http://www.yso.fi/onto/mesh/D000071458

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