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Concept information

Preferred term

Death Domain  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Death Domains

Scope note

  • A conserved protein interaction domain of the death domain superfamily that is structurally similar to the DEATH EFFECTOR DOMAIN and CASPASE RECRUITMENT DOMAIN. Death domains bind each other to form oligomers and occur on DEATH DOMAIN RECEPTORS, where they are required for APOPTOSIS signaling and non-apoptotic functions.

History note

  • 2017

In other languages

URI

http://www.yso.fi/onto/mesh/D000071459

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