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Amino Acids, Peptides, and Proteins > Proteins > Antiviral Restriction Factors > APOBEC-3G Deaminase
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Aminohydrolases > Nucleoside Deaminases > Cytidine Deaminase > APOBEC Deaminases > APOBEC-3G Deaminase

Preferred term

APOBEC-3G Deaminase  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • APOBEC 3G dC dU Editing Enzyme
  • APOBEC-3G dC-dU Editing Enzyme
  • APOBEC3G Deaminase
  • APOBEC 3G Protein
  • APOBEC-3G Protein
  • APOBEC3G Protein
  • APOBEC Related Cytidine Deaminase
  • APOBEC-Related Cytidine Deaminase
  • APOBEC Related Protein
  • APOBEC-Related Protein
  • CEM15 Protein
  • Cytidine Deaminase, APOBEC-Related
  • Deaminase, APOBEC3G

Scope note

  • An APOBEC deaminase that functions as an inhibitor of RETROVIRIDAE replication and inhibits the mobility of RETROTRANSPOSONS via deaminase-dependent and independent mechanisms. It is selective for SINGLE-STRANDED DNA and does not deaminate double-stranded DNA or single or DOUBLE-STRANDED RNA. It exhibits potent antiviral activity against VIF PROTEIN deficient HIV-1 through the creation of hypermutations in the VIRAL DNA. It also has anti-viral activity against SIMIAN IMMUNODEFICIENCY VIRUSES and HEPATITIS B VIRUS.

History note

  • 2017

In other languages

URI

http://www.yso.fi/onto/mesh/D000071480

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