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Enzymes and Coenzymes > Enzymes > DNA Repair Enzymes > AlkB Enzymes > AlkB Homolog 5, RNA Demethylase
... > Enzymes and Coenzymes > Enzymes > Oxidoreductases > Oxygenases > Dioxygenases > AlkB Enzymes > AlkB Homolog 5, RNA Demethylase
... > Enzymes and Coenzymes > Enzymes > Oxidoreductases > Oxidoreductases Acting on CH-NH Group Donors > Oxidoreductases, N-Demethylating > AlkB Homolog 5, RNA Demethylase

Preferred term

AlkB Homolog 5, RNA Demethylase  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • ALKBH5, RNA Demethylase
  • Alkylated DNA Repair Protein AlkB Homolog 5
  • Alpha Ketoglutarate Dependent Dioxygenase AlkB Homolog 5
  • Alpha-Ketoglutarate-Dependent Dioxygenase AlkB Homolog 5
  • Demethylase ALKBH5, RNA
  • RNA Demethylase ALKBH5

Scope note

  • A dioxygenase and alkylation repair homolog that demethylates RNA by oxidative demethylation. It specifically demethylates N(6)-methyladenosine (m6A) RNA, the most common internal modification of MESSENGER RNA in higher eukaryotes. It can also demethylate N(6)-methyladenosine in SINGLE-STRANDED DNA.

History note

  • 2017

In other languages

URI

http://www.yso.fi/onto/mesh/D000071502

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