Concept information
Preferred term
beta-Arrestins
Type
-
Topical Descriptor
Broader concept
Narrower concepts
Entry terms
- beta Arrestin
- beta-Arrestin
Scope note
- Non-visual system arrestins that negatively regulate G-PROTEIN-COUPLED RECEPTORS (GPCRs) and may also function independently of GPCR signaling. They bind and recruit many different signaling factors, including MITOGEN-ACTIVATED PROTEIN KINASES; SRC-FAMILY-KINASES; and FILAMIN to GPCRs and may recognize different phosphorylation states of the receptors to determine the specificity of the cellular response to signaling.
History note
- 2017 (1992)
In other languages
-
Finnish
-
Swedish
URI
http://www.yso.fi/onto/mesh/D000071557
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