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Concept information

Preferred term

beta-Arrestins  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • beta Arrestin
  • beta-Arrestin

Scope note

  • Non-visual system arrestins that negatively regulate G-PROTEIN-COUPLED RECEPTORS (GPCRs) and may also function independently of GPCR signaling. They bind and recruit many different signaling factors, including MITOGEN-ACTIVATED PROTEIN KINASES; SRC-FAMILY-KINASES; and FILAMIN to GPCRs and may recognize different phosphorylation states of the receptors to determine the specificity of the cellular response to signaling.

History note

  • 2017 (1992)

In other languages

URI

http://www.yso.fi/onto/mesh/D000071557

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