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Concept information

Preferred term

Receptor, Notch3  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Neurogenic Locus Notch Homolog Protein 3
  • Notch 3 Protein
  • Notch-3 Protein
  • Notch3 Protein
  • Notch 3 Receptor
  • Notch-3 Receptor
  • Notch3 Receptor

Scope note

  • A notch receptor characterized by a large extracellular domain containing 34 EPIDERMAL GROWTH FACTOR-like repeats. It functions to regulate CELL DIFFERENTIATION; APOPTOSIS; and CELL PROLIFERATION. Mutations in the EGF repeats of Notch-3 are associated with CADASIL.

History note

  • 2017

In other languages

URI

http://www.yso.fi/onto/mesh/D000071656

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