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Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > Poly-ADP-Ribose Binding Proteins > Werner Syndrome Helicase
Amino Acids, Peptides, and Proteins > Proteins > Nuclear Proteins > Poly-ADP-Ribose Binding Proteins > Werner Syndrome Helicase
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Acid Anhydride Hydrolases > Adenosine Triphosphatases > DNA Helicases > RecQ Helicases > Werner Syndrome Helicase
... > Enzymes and Coenzymes > Enzymes > Isomerases > DNA Helicases > RecQ Helicases > Werner Syndrome Helicase
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Esterases > Deoxyribonucleases > Exodeoxyribonucleases > Werner Syndrome Helicase
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Esterases > Exonucleases > Exodeoxyribonucleases > Werner Syndrome Helicase

Preferred term

Werner Syndrome Helicase  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • RECQ3 Protein
  • RECQL2 Protein
  • Werner Syndrome ATP Dependent Helicase
  • Werner Syndrome ATP-Dependent Helicase
  • Werner Syndrome RecQ Like Helicase
  • Werner Syndrome RecQ-Like Helicase

Scope note

  • A DNA-dependent helicase and 3'-5' exonuclease. It has 3'->5' exonuclease activity towards double-stranded DNA with a 5'-overhang and binds preferentially to DNA substrates containing alternate secondary structures, such as replication forks and HOLLIDAY JUNCTIONS. Mutations in the WRN gene are associated with WERNER SYNDROME.

History note

  • 2017

In other languages

URI

http://www.yso.fi/onto/mesh/D000071657

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