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Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Phosphoprotein Phosphatases > Tartrate-Resistant Acid Phosphatase
Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Phosphoprotein Phosphatases > Tartrate-Resistant Acid Phosphatase
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Esterases > Phosphoric Monoester Hydrolases > Phosphoprotein Phosphatases > Tartrate-Resistant Acid Phosphatase
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Esterases > Phosphoric Monoester Hydrolases > Acid Phosphatase > Tartrate-Resistant Acid Phosphatase

Preferred term

Tartrate-Resistant Acid Phosphatase  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • TRAcP

Scope note

  • One of several acid phosphatases in humans, other mammals, plants, and a few prokaryotes. The protein fold of tartrate-resistant acid phosphatase (TRAP) resembles that of the catalytic domain of plant purple acid phosphatase and other serine/threonine-protein phosphatases that also contain a metallophosphoesterase domain. One gene produces the various forms which include purple acid phosphatases from spleen and other tissues. Tartrate-resistant acid phosphatase is a biomarker for pathological states in which it is over-expressed. Such conditions include GAUCHER DISEASE; HODGKIN DISEASE; BONE RESORPTION; and NEOPLASM METASTASIS.

History note

  • 2017 (1995)

In other languages

URI

http://www.yso.fi/onto/mesh/D000071681

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