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Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Guanylate Cyclase > Soluble Guanylyl Cyclase
Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Guanylate Cyclase > Soluble Guanylyl Cyclase
... > Enzymes and Coenzymes > Enzymes > Lyases > Phosphorus-Oxygen Lyases > Guanylate Cyclase > Soluble Guanylyl Cyclase

Preferred term

Soluble Guanylyl Cyclase  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Cyclase, Soluble Guanylate
  • Guanylate Cyclase, Soluble
  • Nitric Oxide Receptor
  • Nitric Oxide Receptors
  • Nitric Oxide Sensitive Guanylyl Cyclase
  • Nitric Oxide-Sensitive Guanylyl Cyclase
  • Oxide Receptor, Nitric
  • Oxide Receptors, Nitric
  • Receptor, Nitric Oxide
  • Soluble Guanylate Cyclase

Scope note

  • A mammalian enzyme composed of a heterodimer of alpha and beta subunits. Each subunit consists of four domains; N-terminal HNOX domain, PAS-like domain, a coiled-coil domain, and a C-terminal catalytic domain. All four domains are homologous proteins with a similar conformation of functional domains. Soluble guanylate cyclase catalyzes the formation of cyclic GMP from GTP, and is a key enzyme of the nitric oxide signaling pathway involved in the regulation of a variety of biological and physiological processes in mammals.

History note

  • 2017 (2016)

In other languages

URI

http://www.yso.fi/onto/mesh/D000071756

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