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... > Chemical Phenomena > Biochemical Phenomena > Molecular Structure > Molecular Conformation > Protein Conformation > Protein Structural Elements > Protein Domains > Protein Interaction Domains and Motifs > BTB-POZ Domain
... > Chemical Phenomena > Biochemical Phenomena > Molecular Structure > Molecular Conformation > Protein Conformation > Protein Structure, Tertiary > Protein Domains > Protein Interaction Domains and Motifs > BTB-POZ Domain

Preferred term

BTB-POZ Domain  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Broad Complex, Tramtrack and Bric a Brac Domain
  • Broad-Complex, Tramtrack and Bric a Brac Domain
  • BTB Domain
  • BTB Domains
  • BTB (POZ) Domain
  • POxvirus and Zinc Finger Domain
  • POZ Domain
  • POZ Domains

Scope note

  • A homodimerization protein interaction domain occurring at the N terminus of proteins that contain multiple copies of either CYS2-HIS2 ZINC FINGERS or KELCH REPEATS. It is characterized by a tightly intertwined dimer with an extensive hydrophobic interface. A surface-exposed groove lined with conserved amino acids is formed at the dimer interface, suggesting a peptide-binding site. Many BTB proteins are transcriptional regulators that are thought to regulate CHROMATIN structure.

History note

  • 2017

In other languages

URI

http://www.yso.fi/onto/mesh/D000071757

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