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Concept information

Preferred term

SMARCB1 Protein  

Type

  • Topical Descriptor

Entry terms

  • BAF47 Protein
  • BRG1 Associated Factor 47 Protein
  • BRG1-Associated Factor 47 Protein
  • Integrase Interactor 1 Protein
  • SNF5 Homolog Protein
  • Swi Snf Related Matrix Associated Actin Dependent Regulator Of Chromatin Subfamily B Member 1
  • Swi-Snf-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin Subfamily B Member 1

Scope note

  • A component of the SWI-SNF CHROMATIN REMODELING complex that functions as a PROTEIN PHOSPHATASE 1 regulator and to stabilize CHROMATIN at PROMOTER REGIONS. It is important for regulating CELL PROLIFERATION and CELL DIFFERENTIATION. Mutations in the SMARCB1 gene are associated with malignant RHABDOID TUMORS.

History note

  • 2017

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URI

http://www.yso.fi/onto/mesh/D000071796

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